Description

3-Amino-5-Chloro-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, functionalized indole derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive amino and ester functional groups, enabling the construction of complex heterocyclic frameworks essential for pharmaceutical discovery. It is primarily sought by research institutions and chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core structure.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic compounds for material science and chemical research.
• Biochemical Probe Development: Serves as a scaffold for creating fluorescent dyes, molecular tags, and other diagnostic reagents.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	3-Amino-5-Chloro-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	889950-17-8
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	Methyl 3-Amino-5-chloro-1H-indole-2-carboxylate; 3-Amino-5-chloroindole-2-carboxylic acid methyl ester; 5-Chloro-3-aminoindole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 3-amino-5-chloro-, methyl ester; 889950-17-8; Methyl 5-chloro-3-amino-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloro-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.