Description

Methyl 3-Amino-5-Fluoro-1-Methyl-1H-Indole-2-Carboxylate is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical manufacturers need this precise intermediate to create new therapeutic agents, leveraging its reactive amino and ester functional groups for further derivatization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorinated indole structure can impart unique biological activity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Fluorinated Compound Library Synthesis: An essential building block for creating diverse screening libraries in drug discovery programs.

Basic Information

Item	Details
Product Name	Methyl 3-Amino-5-Fluoro-1-Methyl-1H-Indole-2-Carboxylate
CAS No.	889950-10-1
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	3-Amino-5-fluoro-1-methyl-1H-indole-2-carboxylic acid methyl ester; Methyl 3-amino-5-fluoro-1-methylindole-2-carboxylate; 5-Fluoro-1-methyl-3-aminoindole-2-carboxylic acid methyl ester; 889950-10-1; 1-Methyl-3-amino-5-fluoroindole-2-carboxylate; 3-Amino-5-fluoro-1-methylindole-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-5-Fluoro-1-Methyl-1H-Indole-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, guaranteeing traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.