Description

tert-Butyl 4-(1H-Indazol-3-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine-indazole core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Core scaffold for the research and synthesis of kinase inhibitors due to the indazole pharmacophore.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological evaluation.
• Process Chemistry: Serves as a critical intermediate in the scale-up and process development of active pharmaceutical ingredients (APIs).
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	tert-Butyl 4-(1H-Indazol-3-Yl)Piperidine-1-Carboxylate
CAS No.	889945-69-1
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(1H-indazol-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1H-indazol-3-yl)piperidine; tert-Butyl 4-(1H-indazol-3-yl)-1-piperidinecarboxylate; 4-(1H-Indazol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; 3-(1-Boc-4-piperidyl)-1H-indazole; 889945-69-1; BOC-4-(1H-Indazol-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Indazol-3-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide material to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.