Description

2-Methylindole-3-Carboxamidine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique indole-derived structure, which serves as a critical precursor for the development of novel pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound Synthesis: Employed in the creation of specific probes and inhibitors for studying enzymatic pathways and cellular signaling processes.
• Agrochemical Research: Serves as an intermediate in the development of new crop protection agents and pesticides with novel modes of action.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental organic synthesis projects and method development.

Basic Information

Product Name	2-Methylindole-3-Carboxamidine
CAS No.	889944-18-7
Molecular Formula	C10H11N3
Molecular Weight	173.21 g/mol
Synonyms	2-Methyl-1H-indole-3-carboximidamide; 3-Carbamimidoyl-2-methyl-1H-indole; 2-Methylindole-3-carboxamidine hydrochloride (salt form); 2-Methyl-3-amidinoindole; SKF-86002 (related analog); Indole-3-carboxamidine derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Methylindole-3-Carboxamidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and development applications. A detailed Certificate of Analysis (COA) including results for assay, purity (HPLC), and identification is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.