Description

n-Hydroxy-5-Methoxy-1H-Indole-3-Carboxamidine is a specialized indole derivative with a unique carboxamidine functional group. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Enzyme Inhibitor Development: Serves as a precursor or core scaffold for designing enzyme inhibitors due to its metal-chelating potential.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.
• Pre-clinical Development: Integrated into the synthesis of compounds for pre-clinical evaluation and toxicology studies.

Basic Information

Product Name	n-Hydroxy-5-Methoxy-1H-Indole-3-Carboxamidine
CAS No.	889943-79-7
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	5-Methoxy-1H-indole-3-carboximidic acid, N-hydroxy-; N-Hydroxy-5-methoxy-1H-indole-3-carboxamidine; 5-Methoxy-1H-indole-3-carboximidic acid, hydroxy-; 1H-Indole-3-carboximidic acid, N-hydroxy-5-methoxy-; 3-(N-Hydroxycarbamimidoyl)-5-methoxy-1H-indole; 5-Methoxy-3-(N-hydroxycarbamimidoyl)indole
EINECS	Contact for details

Quality Control

Our n-Hydroxy-5-Methoxy-1H-Indole-3-Carboxamidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.