Description

n-Hydroxy-5-Methyl-1H-Indole-3-Carboximidamide is a specialized indole derivative that serves as a crucial synthetic intermediate and building block in advanced organic chemistry. Its unique molecular scaffold, featuring both an indole core and a reactive amidoxime functional group, makes it a valuable precursor for the development of novel pharmacologically active compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery, medicinal chemistry, and the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the creation of new pesticides and herbicides with specific biological activity.
• Biochemical Tool Compound: Utilized in life science research to study enzyme inhibition and receptor-ligand interactions.
• Organic Synthesis: Acts as a versatile reagent for constructing complex heterocyclic frameworks and functionalized indole derivatives.
• Material Science Precursor: Potential use in the development of organic electronic materials and advanced polymers.

Basic Information

Product Name	n-Hydroxy-5-Methyl-1H-Indole-3-Carboximidamide
CAS No.	889943-61-7
Molecular Formula	C10H11N3O
Molecular Weight	189.21 g/mol
Synonyms	5-Methyl-1H-indole-3-carboximidamide, N-hydroxy-; 3-Amidino-5-methylindole N-oxide; 5-Methylindole-3-carboxamidoxime; 1H-Indole-3-carboximidamide, N-hydroxy-5-methyl-; 5-Methyl-1H-indole-3-carboxamidoxime; N-Hydroxy-5-methyl-1H-indole-3-carboximidamide; 5-Methylindole-3-amidoxime
EINECS	Contact for details

Quality Control

Our n-Hydroxy-5-Methyl-1H-Indole-3-Carboximidamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.