Description

n-Hydroxy-4-Chloro-1H-Indole-3-Carboxamidine is a high-purity, synthetically derived indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemical discovery, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Agrochemical Development: Serves as a building block for creating new pesticides, herbicides, or plant growth regulators with enhanced efficacy.
• Biochemical Probe Synthesis: Employed in the creation of specialized probes and inhibitors for studying biological pathways and enzyme functions.
• Organic Synthesis Reagent: Utilized in complex multi-step synthetic routes to construct intricate indole-containing molecular architectures.
• Academic & Industrial R&D: Essential for exploratory research in universities and corporate labs focused on heterocyclic and fine chemical innovation.

Basic Information

Product Name	n-Hydroxy-4-Chloro-1H-Indole-3-Carboxamidine
CAS No.	889942-75-0
Molecular Formula	C9H8ClN3O
Molecular Weight	209.63 g/mol
Synonyms	4-Chloro-1H-indole-3-carboximidamide, N-hydroxy-; 4-Chloro-N-hydroxy-1H-indole-3-carboximidamide; 4-Chloro-1H-indole-3-carboxamidine, N-hydroxy-; 889942-75-0; n-Hydroxy-4-chloroindole-3-carboxamidine; 4-Chloro-1H-indole-3-carboxylic acid amidoxime; 3-(N-Hydroxyamidino)-4-chloroindole
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-Chloro-1H-Indole-3-Carboxamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.