Description

4-Chloro-1H-Indole-3-Carbonitrile is a versatile and high-value halogenated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both chloro and cyano substituents, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it is used to introduce key pharmacophores and modulate biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials with unique optoelectronic properties.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or labeling agent in the design of chemical probes and enzyme inhibitors for biological pathway studies.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in organic synthesis and heterocyclic chemistry.
• Dye & Pigment Intermediate: Acts as a precursor for synthesizing specialized indole-based dyes and colorants.

Basic Information

Product Name	4-Chloro-1H-Indole-3-Carbonitrile
CAS No.	889942-73-8
Molecular Formula	C9H5ClN2
Molecular Weight	176.60 g/mol
Synonyms	4-Chloro-1H-indole-3-carbonitrile; 4-Chloroindole-3-carbonitrile; 3-Cyano-4-chloroindole; 4-Chloro-3-cyanoindole; 1H-Indole-3-carbonitrile, 4-chloro-; 889942-73-8; 4-Cl-1H-Indole-3-CN
EINECS	Contact for details

Quality Control

Our 4-Chloro-1H-Indole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.