Description

2-[4-(4-Fluoro-Phenyl)-Piperazin-1-Ylmethyl]-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining indole and fluorophenylpiperazine moieties. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology fields. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting serotonin and dopamine receptor pathways.
• Neurological Research: Used in preclinical studies for developing novel antipsychotic, antidepressant, or anxiolytic compounds.
• Oncological Research: Serves as a precursor in the development of targeted cancer therapies due to its specific chemical scaffold.
• Chemical Reference Standard: Employed as a high-purity standard in analytical method development and quality control for related compounds.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and medicinal chemistry.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in bespoke, multi-step synthetic routes.

Basic Information

Product Name	2-[4-(4-Fluoro-Phenyl)-Piperazin-1-Ylmethyl]-1H-Indole
CAS No.	889868-67-1
Molecular Formula	C19H20FN3
Molecular Weight	309.38 g/mol
Synonyms	1H-Indole, 2-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-; 2-((4-(4-Fluorophenyl)piperazin-1-yl)methyl)-1H-indole; 2-[[4-(4-Fluorophenyl)piperazin-1-yl]methyl]indole; 2-(4-(4-Fluorophenyl)piperazin-1-ylmethyl)-1H-indole; 889868-67-1; 4-(4-Fluorophenyl)-1-(1H-indol-2-ylmethyl)piperazine
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(4-Fluoro-Phenyl)-Piperazin-1-Ylmethyl]-1H-Indole is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products meet the stringent requirements for pharmaceutical R&D and are supported by a detailed Certificate of Analysis (COA) for each lot, which includes data from HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our global clientele in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.