Description

7-Bromo-3-difluoromethyl-1,2,3,4-tetrahydroisoquinoline is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the difluoromethyl and bromo-substituted isoquinoline scaffold.
• Material Science: Acts as a building block for advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex fluorinated heterocycles.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and reaction mechanisms involving halogenated and fluorinated compounds.

Basic Information

Product Name	7-Bromo-3-difluoromethyl-1,2,3,4-tetrahydroisoquinoline
CAS No.	889861-17-0
Molecular Formula	C11H10BrF2N
Molecular Weight	274.11 g/mol
Synonyms	7-Bromo-3-(difluoromethyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-bromo-3-(difluoromethyl)isoquinoline; 889861-17-0; 7-Bromo-3-difluoromethyl-THIQ; 3-(Difluoromethyl)-7-bromo-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-difluoromethyl-1,2,3,4-tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.