Description

1-(4-(Benzyloxy)-1-(Phenylsulfonyl)-1H-Indol-2-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate with the CAS number 889675-05-2. This compound is a critical building block in modern organic synthesis, valued for its unique indole-based sulfonamide structure that enables complex molecular transformations. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing indole and sulfonamide-containing molecular frameworks.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Specialty Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other performance chemicals where specific heterocyclic structures are required.

Basic Information

Product Name	1-(4-(Benzyloxy)-1-(Phenylsulfonyl)-1H-Indol-2-Yl)Ethanone
CAS No.	889675-05-2
Molecular Formula	C23H19NO4S
Molecular Weight	405.46 g/mol
Synonyms	2-Acetyl-4-benzyloxy-1-phenylsulfonylindole; 1-[4-(Benzyloxy)-1-(phenylsulfonyl)-1H-indol-2-yl]ethanone; Ethanone, 1-[4-(benzyloxy)-1-(phenylsulfonyl)-1H-indol-2-yl]-; 889675-05-2; 4-Benzyloxy-1-phenylsulfonyl-2-acetylindole; 2-Acetyl-1-(phenylsulfonyl)-4-(benzyloxy)indole; 1-(4-Benzyloxy-1-phenylsulfonyl-1H-indol-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(4-(Benzyloxy)-1-(Phenylsulfonyl)-1H-Indol-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.