Description

Ethyl 3-o-Benzyl-4,6-o-Benzylidene-2-o-Levulinoyl-B-D-Thioglucopyranoside is a sophisticated, multi-protected thioglycoside building block of significant value in synthetic organic chemistry. This compound matters because it provides a versatile and reactive glycosyl donor platform, crucial for the controlled synthesis of complex carbohydrate mimetics and glycoconjugates. It is primarily needed by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, including antiviral agents, vaccines, and targeted drug delivery systems.

Application

• Glycosylation Reagent: Serves as a key thioglycosyl donor in the stereoselective synthesis of O-glycosides, C-glycosides, and S-glycosides.
• Oligosaccharide Assembly: A critical intermediate in the automated or solution-phase synthesis of complex oligosaccharides and glycans for biological studies.
• Glycoconjugate Development: Used to create glycopeptides, glycolipids, and other glycoconjugates for immunological and drug discovery research.
• Carbohydrate Mimetic Synthesis: Enables the construction of glycomimetics where the sugar scaffold is modified to enhance stability and biological activity.
• Pharmaceutical Intermediate: Acts as a building block in the research and development stages of novel carbohydrate-based pharmaceuticals.
• Chemical Biology Probes: Utilized in the synthesis of labeled carbohydrate probes for studying glycosylation processes and carbohydrate-protein interactions.

Basic Information

Product Name	Ethyl 3-o-Benzyl-4,6-o-Benzylidene-2-o-Levulinoyl-B-D-Thioglucopyranoside
CAS No.	889129-00-4
Molecular Formula	C29H34O7S
Molecular Weight	526.64 g/mol
Synonyms	Ethyl 2-O-Levulinoyl-3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, ethyl 2-O-(4-oxopentanoyl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, (2R,3S,4R,5R,6R)-; Ethyl 1-Thio-β-D-glucopyranoside derivative; Protected Thioglucoside Donor; Benzylidene Acetal Protected Thioglycoside; Levulinoyl Ester Protected Glycosyl Donor
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development chemicals. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.