Description

5-Ethynyl-1H-Indole is a versatile and high-value heterocyclic building block featuring both an indole core and a reactive ethynyl group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the creation of novel polymers or molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted drug candidates, particularly in oncology and neurology research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides with specific biological activity.
• Material Science Building Block: Employed in the creation of advanced organic materials, including conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Acts as a versatile handle for "click chemistry" (e.g., CuAAC reactions) to label or conjugate biomolecules for diagnostic and research purposes.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A fundamental reagent for exploratory synthetic chemistry and the development of new chemical methodologies.

Basic Information

Product Name	5-Ethynyl-1H-Indole
CAS No.	889108-48-9
Molecular Formula	C10H7N
Molecular Weight	141.17 g/mol
Synonyms	5-Ethynylindole; 1H-Indole, 5-ethynyl-; 5-Ethynyl-1H-indole; 5-Ethynylindole; Indole, 5-ethynyl-
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-1H-Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.