Description

n-(5-tert-Butyl-1,3,4-Thiadiazol-2-Yl)-5-Oxo-1-Phenylpyrrolidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and development of new generation pesticides and herbicides, leveraging its thiadiazole moiety.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.
• Biochemical Probe Synthesis: Utilized in the creation of specialized probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	n-(5-tert-Butyl-1,3,4-Thiadiazol-2-Yl)-5-Oxo-1-Phenylpyrrolidine-3-Carboxamide
CAS No.	887673-17-8
Molecular Formula	C₁₇H₂₀N₄O₂S
Molecular Weight	344.43 g/mol
Synonyms	5-Oxo-1-phenyl-N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-3-pyrrolidinecarboxamide; 1-Phenyl-5-oxo-N-[5-(tert-butyl)-1,3,4-thiadiazol-2-yl]pyrrolidine-3-carboxamide; 887673-17-8; tert-Butyl Thiadiazole Pyrrolidinone Carboxamide; 5-tert-Butyl-1,3,4-thiadiazol-2-amine derivative
EINECS	Contact for details

Quality Control

Our production of n-(5-tert-Butyl-1,3,4-Thiadiazol-2-Yl)-5-Oxo-1-Phenylpyrrolidine-3-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.