Description

5-Cyanoamino-Indazole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a protected carboxylic acid group and a versatile cyanoamino moiety for further functionalization. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel indazole-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• API Synthesis: Serves as a precursor in the multi-step manufacturing of complex active pharmaceutical ingredients.
• Biochemical Tool Compound: Employed in the development of biochemical probes and assay standards for pharmacological screening.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	5-Cyanoamino-Indazole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887594-17-4
Molecular Formula	C13H14N4O2
Molecular Weight	258.28 g/mol
Synonyms	tert-Butyl 5-cyanoamino-1H-indazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 5-(aminocarbonyl)-, 1,1-dimethylethyl ester; 5-Carbamoyl-1H-indazole-1-carboxylic acid tert-butyl ester; 5-Cyanoamino-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester; BOC-protected 5-cyanoaminoindazole; 887594-17-4
EINECS	Contact for details

Quality Control

Every batch of 5-Cyanoamino-Indazole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.