Description

5-Amino-Isoquinoline-8-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both an amino and a carboxylic acid group on the isoquinoline scaffold, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic core.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Chemical Biology: Utilized as a probe or scaffold in the design of molecular tools for studying biological systems.
• Custom Synthesis: A valuable building block for contract research organizations (CROs) and CDMOs performing bespoke synthetic chemistry.

Basic Information

Product Name	5-Amino-Isoquinoline-8-Carboxylic Acid
CAS No.	887591-08-4
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	5-Aminoisoquinoline-8-carboxylic acid; 8-Carboxy-5-aminoisoquinoline; 5-Amino-8-isoquinolinecarboxylic acid; AIQCA; 5-Amino-8-carboxyisoquinoline; Isoquinoline-8-carboxylic acid, 5-amino-; 887591-08-4
EINECS	Contact for details

Quality Control

Our 5-Amino-Isoquinoline-8-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity by HPLC, and identification. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.