Description

6-Amino-3-Morpholin-4-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on oncology, neurology, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Development: Used in the process development and scale-up manufacturing of new chemical entities (NCEs).
• Biochemical Research: Employed as a tool compound for studying biological pathways and enzyme interactions in vitro.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for research purposes.

Basic Information

Product Name	6-Amino-3-Morpholin-4-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887591-01-7
Molecular Formula	C18H26N4O3
Molecular Weight	346.43 g/mol
Synonyms	tert-Butyl 6-amino-3-[(morpholin-4-yl)methyl]-1H-indazole-1-carboxylate; 6-Amino-3-(morpholinomethyl)-1H-indazole-1-carboxylic acid tert-butyl ester; 1H-Indazole-1-carboxylic acid, 6-amino-3-[(4-morpholinyl)methyl]-, 1,1-dimethylethyl ester; 887591-01-7; 6-Amino-3-morpholin-4-ylmethyl-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 6-amino-3-(morpholin-4-ylmethyl)indazole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Morpholin-4-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.