Description

6-Amino-3-Pyrrolidin-1-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, particularly for targeting specific biological pathways. It is essential for research and production in the pharmaceutical and biotechnology industries, where precise chemical architecture is required for developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its specific indazole and pyrrolidine motifs.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for creating potent and selective kinase inhibitors for targeted cancer therapies.
• Chemical Biology & Probe Development: Employed in the design of molecular probes to study protein function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic & Institutional Research: Utilized in university and institutional labs for medicinal chemistry programs and novel compound library generation.

Basic Information

Product Name	6-Amino-3-Pyrrolidin-1-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887590-95-6
Molecular Formula	C18H26N4O2
Molecular Weight	330.43 g/mol
Synonyms	tert-Butyl 6-amino-3-[(pyrrolidin-1-yl)methyl]-1H-indazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 6-amino-3-[(1-pyrrolidinyl)methyl]-, 1,1-dimethylethyl ester; 6-Amino-3-(pyrrolidin-1-ylmethyl)-1H-indazole-1-carboxylic acid tert-butyl ester; BOC-6-Amino-3-pyrrolidinylmethylindazole; 887590-95-6; 6-Amino-3-(1-pyrrolidinylmethyl)-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Pyrrolidin-1-Ylmethyl-Indazole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.