Description

1-(2-Bromoethyl)-2,3,4-Trifluorobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring a reactive bromoethyl side chain and a trifluoromethyl-substituted benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly those requiring the unique physicochemical properties imparted by fluorine atoms.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology drugs where fluorine substitution is beneficial.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Electronics: Acts as a starting material for synthesizing fluorinated organic semiconductors and charge-transport materials used in OLEDs and solar cells.
• Cross-Coupling Reactions: The bromoethyl moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form more complex biaryl structures.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-(2-Bromoethyl)-2,3,4-Trifluorobenzene
CAS No.	887586-25-6
Molecular Formula	C8H5BrF3
Molecular Weight	247.03 g/mol
Synonyms	2-(2,3,4-Trifluorophenyl)ethyl Bromide; (2-Bromoethyl)-2,3,4-trifluorobenzene; 2,3,4-Trifluoro-β-bromoethylbenzene; 1-Bromo-2-(2,3,4-trifluorophenyl)ethane; α-Bromo-2,3,4-trifluorotoluene (related); 2,3,4-Trifluorophenethyl Bromide
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethyl)-2,3,4-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR, IR, and GC-MS. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our commitment is to deliver material of consistent high purity and reliable performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.