Description

6-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a reactive aminomethyl group and a tert-butyl ester protecting group, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex indole-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Research: Used to incorporate indole motifs into peptide backbones, creating novel peptidomimetics with enhanced biological activity and stability.
• Agrochemical Synthesis: Serves as a precursor for developing new generation herbicides and fungicides that leverage the indole pharmacophore.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags and molecular probes to study biological pathways.
• Academic & Process Chemistry: A versatile reagent for methodological development and scale-up studies in organic synthesis laboratories.

Basic Information

Product Name	6-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887584-21-6
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	tert-Butyl 6-(Aminomethyl)-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 6-(aminomethyl)-, 1,1-dimethylethyl ester; 6-(Aminomethyl)indole-1-carboxylic Acid tert-Butyl Ester; Boc-6-Aminomethylindole; 1-Boc-6-aminomethylindole; 6-Aminomethyl-1-Boc-indole; (1-(tert-Butoxycarbonyl)-1H-indol-6-yl)methanamine
EINECS	Contact for details

Quality Control

Every batch of 6-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.