Description

5-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive amine functionality while the tert-butyl ester group offers orthogonal protection, enabling precise, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Peptidomimetic Chemistry: Used to incorporate indole-based scaffolds into peptide analogs to enhance stability and biological activity.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or functionalizing agent for creating specialized polymers with unique electronic or photophysical properties.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-gram to kilogram-scale production.

Basic Information

Product Name	5-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887584-14-7
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 5-(aminomethyl)-, 1,1-dimethylethyl ester; tert-Butyl 5-(aminomethyl)-1H-indole-1-carboxylate; 5-(Aminomethyl)indole-1-carboxylic Acid tert-Butyl Ester; Boc-5-Aminomethylindole; 1-Boc-5-aminomethylindole; 5-Aminomethyl-1-Boc-indole; 5-(Aminomethyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 5-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.