Description

3-Aminomethyl-1H-Indole-5-Carboxylic Acid Methyl Ester is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive aminomethyl group and a protected carboxylic acid, makes it an invaluable scaffold for constructing complex heterocyclic molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Monomer or functional unit for creating specialty polymers, dyes, and advanced organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Aminomethyl-1H-Indole-5-Carboxylic Acid Methyl Ester
CAS No.	887582-73-2
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	Methyl 3-(aminomethyl)-1H-indole-5-carboxylate; 5-(Methoxycarbonyl)-1H-indole-3-methanamine; 1H-Indole-5-carboxylic acid, 3-(aminomethyl)-, methyl ester; 3-Aminomethylindole-5-carboxylic acid methyl ester; 3-(Aminomethyl)-1H-indole-5-carboxylic acid methyl ester; Methyl 3-aminomethylindole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Aminomethyl-1H-Indole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.