Description

1H-Indole-2-Carboxylic Acid, 7-Chloro-5-Fluoro-, Ethyl Ester is a high-value fluorinated indole derivative, a crucial synthetic intermediate in modern organic chemistry. Its core value lies in its versatile molecular scaffold, which is designed for the efficient construction of complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders and cancer.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the indole core.
• Material Science Precursor: Serves as a starting material for creating specialized organic compounds used in electronic materials or advanced polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for structure-activity relationship (SAR) studies.
• Fluorinated Compound Library Synthesis: A valuable reagent for constructing libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 7-Chloro-5-Fluoro-, Ethyl Ester
CAS No.	887578-55-4
Molecular Formula	C12H11ClFNO2
Molecular Weight	255.67 g/mol
Synonyms	7-Chloro-5-fluoro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 7-chloro-5-fluoro-1H-indole-2-carboxylate; 7-Chloro-5-fluoroindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 7-chloro-5-fluoro-, ethyl ester; 887578-55-4; Ethyl 7-chloro-5-fluoroindole-2-carboxylate; 7-Chloro-5-fluoro-1H-indole-2-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 7-Chloro-5-Fluoro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.