Description

6-(Trifluoromethyl)-1H-Indazole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its indazole core, nitrile group, and trifluoromethyl substituent. This compound matters for its critical role in modern medicinal chemistry and agrochemical research, where it serves as a privileged scaffold for designing novel bioactive molecules. Pharmaceutical and agrochemical R&D teams need it for the synthesis of potential drug candidates and advanced crop protection agents, leveraging its unique physicochemical properties to modulate potency, selectivity, and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for advanced organic electronic materials and functional polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and diagnostic development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	6-(Trifluoromethyl)-1H-Indazole-3-Carbonitrile
CAS No.	887577-45-9
Molecular Formula	C9H4F3N3
Molecular Weight	211.15 g/mol
Synonyms	6-(Trifluoromethyl)-1H-indazole-3-carbonitrile; 6-(Trifluoromethyl)-3-cyano-1H-indazole; 3-Cyano-6-(trifluoromethyl)-1H-indazole; 1H-Indazole-3-carbonitrile, 6-(trifluoromethyl)-; 887577-45-9
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-1H-Indazole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided to guarantee supply reliability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.