Description

1H-Indole-6-Carboxylic Acid, 3-Formyl- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique indole scaffold bearing both carboxylic acid and formyl functional groups enables the precise construction of complex molecular architectures. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require specific indole-based structures.
• Ligand Synthesis: Employed for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs) due to its chelating potential.
• Fluorescent Dye & Sensor Development: Acts as a core structure for synthesizing advanced organic fluorophores and chemical sensors.
• Peptidomimetics & Bioconjugation: The carboxylic acid and aldehyde groups facilitate its use in constructing peptide analogs and for site-specific bioconjugation strategies.
• Academic & Contract Research: A vital reagent for methodological development and exploratory chemistry in academic and contract research organizations (CROs).

Basic Information

Product Name	1H-Indole-6-Carboxylic Acid, 3-Formyl-
CAS No.	887576-06-9
Molecular Formula	C10H7NO3
Molecular Weight	189.17 g/mol
Synonyms	3-Formyl-1H-indole-6-carboxylic acid; 6-Carboxy-3-formylindole; 3-Formylindole-6-carboxylic acid; 1H-Indole-6-carboxaldehyde-3-carboxylic acid; 3-Carboxy-6-formylindole; 6-Formylindole-3-carboxylic acid (positional isomer); Indole-3,6-dicarboxaldehyde (reduced form derivative); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carboxylic Acid, 3-Formyl- is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.