Description

6-Iodo-4-Hydroxy-3-Indazolecarboxaldehyde is a halogenated indazole derivative that serves as a versatile and high-value synthetic building block. This compound is particularly significant for its role in medicinal chemistry and pharmaceutical research, where it is used to construct complex molecules with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a building block for creating novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized heterocycles.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Iodo-4-Hydroxy-3-Indazolecarboxaldehyde
CAS No.	887570-50-5
Molecular Formula	C8H5IN2O2
Molecular Weight	288.04 g/mol
Synonyms	6-Iodo-4-hydroxy-1H-indazole-3-carboxaldehyde; 4-Hydroxy-6-iodo-1H-indazole-3-carbaldehyde; 6-Iodo-4-hydroxyindazole-3-carboxaldehyde; 3-Formyl-6-iodo-4-hydroxy-1H-indazole; 6-Iodo-4-hydroxy-1H-indazole-3-carbaldehyde; 887570-50-5; 6-Iodo-4-hydroxyindazole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Iodo-4-Hydroxy-3-Indazolecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality assurance supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.