Description

3-Chloro-4-Hydroxy-6-Iodoindazole is a high-purity halogenated indazole derivative, a key heterocyclic building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for medicinal chemistry research and the development of novel pharmaceutical intermediates. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active compounds.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Acts as a building block for creating novel active ingredients in crop protection and pesticide formulations.
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science Research: Potential precursor for advanced organic electronic materials and functional polymers due to its halogenated indazole core.

Basic Information

Product Name	3-Chloro-4-Hydroxy-6-Iodoindazole
CAS No.	887570-38-9
Molecular Formula	C7H4ClIN2O
Molecular Weight	294.48 g/mol
Synonyms	6-Iodo-3-chloro-1H-indazol-4-ol; 3-Chloro-4-hydroxy-6-iodo-1H-indazole; 4-Hydroxy-3-chloro-6-iodoindazole; 1H-Indazol-4-ol, 3-chloro-6-iodo-; 3-Chloro-6-iodo-1H-indazol-4-ol; 6-Iodo-3-chloroindazol-4-ol; 887570-38-9 (CAS Name)
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-6-Iodoindazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.