Description

4-Chloro-6-Hydroxy-3-(1H)Indazole Carboxaldehyde is a versatile and high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both a reactive aldehyde group and a halogenated indazole core, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery of novel small-molecule therapeutics, particularly in oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents.
• Material Science: Can be utilized in the development of specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations requiring high-quality, custom synthetic building blocks.

Basic Information

Product Name	4-Chloro-6-Hydroxy-3-(1H)Indazole Carboxaldehyde
CAS No.	887569-90-6
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	4-Chloro-6-hydroxy-1H-indazole-3-carbaldehyde; 4-Chloro-6-hydroxyindazole-3-carboxaldehyde; 3-Formyl-4-chloro-6-hydroxyindazole; 1H-Indazole-3-carboxaldehyde, 4-chloro-6-hydroxy-; 4-Chloro-6-hydroxy-1H-indazole-3-carbaldehyde; 887569-90-6; 4-Cl-6-OH-indazole-3-CHO
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Hydroxy-3-(1H)Indazole Carboxaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and MS. Our standard grade meets typical research purity specifications, and we can support development with analytical method validation and stability data upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.