Description

6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers developing next-generation treatments in oncology, inflammation, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile indazole scaffold.
• API Development: Serves as a core structural unit in the development of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Item	Detail
Product Name	6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxylic Acid
CAS No.	887569-75-7
Molecular Formula	C8H5ClN2O3
Molecular Weight	212.59 g/mol
Synonyms	6-Chloro-4-hydroxy-1H-indazole-3-carboxylic acid; 6-Chloro-4-hydroxyindazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 6-chloro-4-hydroxy-; 887569-75-7; 6-Chloro-4-hydroxy-1H-indazole-3-carboxylate; 4-Hydroxy-6-chloro-1H-indazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.