Description

3-Chloro-6-Fluoro-4-Methoxyindazole is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique indazole core, substituted with chlorine, fluorine, and methoxy groups, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the biological activity of the indazole scaffold.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and liquid crystals due to its rigid, planar structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-6-Fluoro-4-Methoxyindazole
CAS No.	887569-49-5
Molecular Formula	C8H6ClFN2O
Molecular Weight	200.60 g/mol
Synonyms	4-Methoxy-3-chloro-6-fluoroindazole; 6-Fluoro-4-methoxy-3-chloro-1H-indazole; 3-Chloro-6-fluoro-4-methoxy-1H-indazole; 1H-Indazole, 3-chloro-6-fluoro-4-methoxy-; 887569-49-5; 3-Chloro-6-fluoro-4-methoxy-1H-indazole; 4-Methoxy-3-chloro-6-fluoro-1H-indazole
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Fluoro-4-Methoxyindazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.