Description

4-Fluoro-6-Hydroxy-3-Chloro (1H)Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated and hydroxylated indazole core structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, leveraging its halogenated indazole scaffold.
• Material Science Research: Serves as a building block for advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of complex heterocyclic libraries.
• Custom Synthesis Starting Material: Provides a versatile, functionalized core for contract manufacturing organizations (CMOs) performing bespoke synthesis for clients.

Basic Information

Item	Details
Product Name	4-Fluoro-6-Hydroxy-3-Chloro (1H)Indazole
CAS No.	887569-25-7
Molecular Formula	C7H4ClFN2O
Molecular Weight	186.57 g/mol
Synonyms	3-Chloro-4-fluoro-6-hydroxy-1H-indazole; 4-Fluoro-6-hydroxy-3-chloro-1H-indazole; 1H-Indazole, 3-chloro-4-fluoro-6-hydroxy-; 6-Hydroxy-3-chloro-4-fluoroindazole; 3-Chloro-4-fluoro-6-hydroxyindazole; 4-Fluoro-3-chloro-6-hydroxy-1H-indazole; CAS 887569-25-7
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-6-Hydroxy-3-Chloro (1H)Indazole is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.