Description

2-Chloro-1-(2,5-Dimethyl-1H-Indol-3-Yl)Ethanone is a versatile and high-value indole-based building block, essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for the development of complex pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers engaged in the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides that leverage the indole scaffold for enhanced biological activity.
• Material Science Research: Employed in the synthesis of organic semiconductors and advanced functional materials due to its electron-rich indole core.
• Academic & Contract Research: Serves as a fundamental building block in university and CRO settings for method development and exploration of new chemical spaces.
• Dye & Pigment Precursor: Utilized in the synthesis of specialized indole-based dyes and colorants.

Basic Information

Product Name	2-Chloro-1-(2,5-Dimethyl-1H-Indol-3-Yl)Ethanone
CAS No.	887569-01-9
Molecular Formula	C₁₂H₁₂ClNO
Molecular Weight	221.68 g/mol
Synonyms	3-Acetyl-2,5-dimethyl-1H-indole-3-carbonyl chloride (common misnomer); 2-Chloro-1-(2,5-dimethyl-1H-indol-3-yl)ethan-1-one; 2',5'-Dimethyl-3-acetylindole-2-carbonyl chloride; 3-(2-Chloroacetyl)-2,5-dimethyl-1H-indole; 2,5-Dimethyl-3-(2-chloroacetyl)indole; 2-Chloro-1-(2,5-dimethylindol-3-yl)ethanone; α-Chloro-2,5-dimethyl-3-indolyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2,5-Dimethyl-1H-Indol-3-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.