Description

6-Bromo-3-Iodo-4-Methoxy-1H-Indazole is a high-value halogenated indazole derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique structure, featuring bromine and iodine substituents at strategic positions, makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile halogen handles for further functionalization via cross-coupling reactions.
• Agrochemical Research: Serves as a building block for synthesizing new pesticides and herbicides with potential novel modes of action.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers where the indazole core contributes specific electronic properties.

Basic Information

Product Name	6-Bromo-3-Iodo-4-Methoxy-1H-Indazole
CAS No.	887568-69-6
Molecular Formula	C8H6BrIN2O
Molecular Weight	352.96 g/mol
Synonyms	4-Methoxy-6-bromo-3-iodo-1H-indazole; 1H-Indazole, 6-bromo-3-iodo-4-methoxy-; 6-Bromo-3-iodo-4-methoxyindazole; 3-Iodo-6-bromo-4-methoxy-1H-indazole; 4-Methoxy-3-iodo-6-bromo-1H-indazole; 6-Bromo-4-methoxy-3-iodo-1H-indazole; CAS 887568-69-6
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Iodo-4-Methoxy-1H-Indazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.