Description

4-Bromo-6-Iodo-3-(1H)Indazole Carboxylic Acid is a high-purity, multi-halogenated indazole derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for medicinal chemistry research, particularly in the development of kinase inhibitors and other targeted therapeutic agents. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and biological pathways.
• Agrochemical Synthesis: Potential intermediate in the research and development of new active ingredients for crop protection.
• Material Science: Building block for advanced organic materials and functional polymers requiring halogenated heterocyclic components.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	4-Bromo-6-Iodo-3-(1H)Indazole Carboxylic Acid
CAS No.	887568-55-0
Molecular Formula	C8H4BrIN2O2
Molecular Weight	366.94 g/mol
Synonyms	4-Bromo-6-iodo-1H-indazole-3-carboxylic acid; 3-Carboxy-4-bromo-6-iodoindazole; 4-Bromo-6-iodoindazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 4-bromo-6-iodo-; 4-Br-6-I-3-(1H)-indazole-COOH; 887568-55-0; AI3-52375; ZINC000103014535
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Iodo-3-(1H)Indazole Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.