Description

3-Bromo-4-Chloro-6-Iodo (1H)Indazole is a high-value, multi-halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, which provides multiple reactive sites for selective functionalization, enabling the rapid construction of complex chemical libraries. It is primarily needed by medicinal chemistry and pharmaceutical R&D teams for the development of novel drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and high-throughput screening to identify promising lead compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging its halogenated indazole core for bioactivity.
• Material Science Precursor: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient character.
• Chemical Biology Probe: Acts as a core structure for designing molecular probes and tags to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the global life sciences industry.

Basic Information

Product Name	3-Bromo-4-Chloro-6-Iodo (1H)Indazole
CAS No.	887568-22-1
Molecular Formula	C7H3BrClIN2
Molecular Weight	356.37 g/mol
Synonyms	3-Bromo-4-chloro-6-iodo-1H-indazole; 1H-Indazole, 3-bromo-4-chloro-6-iodo-; 6-Iodo-3-bromo-4-chloro-1H-indazole; 4-Chloro-3-bromo-6-iodoindazole; 3-Bromo-4-chloro-6-iodoindazole; BCI-Indazole derivative; Multi-halogenated indazole scaffold
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-6-Iodo (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.