Description

6-Bromo-4-Chloro-3-Iodo (1H)Indazole is a high-purity, multi-halogenated indazole derivative, a crucial advanced intermediate in modern organic synthesis. Its complex halogenated structure makes it an indispensable building block for constructing sophisticated molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates, leveraging its halogen handles for further functionalization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the indazole core provides a bioactive scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge transport materials.
• Chemical Biology Probe Development: Utilized in creating tagged molecular probes for studying enzyme function and biological pathways due to its modifiable halogen sites.
• Cross-Coupling Reactions: The bromo and iodo substituents are excellent substrates for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig).
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological activity screening.

Basic Information

Product Name	6-Bromo-4-Chloro-3-Iodo (1H)Indazole
CAS No.	887568-16-3
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.37 g/mol
Synonyms	6-Bromo-4-chloro-3-iodo-1H-indazole; 1H-Indazole, 6-bromo-4-chloro-3-iodo-; 3-Iodo-6-bromo-4-chloro-1H-indazole; 4-Chloro-6-bromo-3-iodo-1H-indazole; 6-Bromo-4-chloro-3-iodoindazole; (1H)-Indazole, 6-bromo-4-chloro-3-iodo-; BCI-Indazole derivative
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Chloro-3-Iodo (1H)Indazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality protocols are designed to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.