Description

6-Bromo-4-Fluoro-3-Hydroxyindazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique halogenated indazole scaffold provides a versatile platform for constructing complex molecules, particularly in the development of new active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need this precise intermediate to create novel drug candidates targeting a range of therapeutic areas, leveraging its reactive bromo and fluoro substituents for further functionalization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive indazole core.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays and proteomics research.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploratory synthetic chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of more complex, proprietary compounds for clients.

Basic Information

Product Name	6-Bromo-4-Fluoro-3-Hydroxyindazole
CAS No.	887568-01-6
Molecular Formula	C7H4BrFN2O
Molecular Weight	231.02 g/mol
Synonyms	6-Bromo-4-fluoro-1H-indazol-3-ol; 4-Fluoro-6-bromo-1H-indazol-3-ol; 3-Hydroxy-6-bromo-4-fluoroindazole; 6-Bromo-4-fluoroindazol-3-ol; 887568-01-6; 6-Br-4-F-3-OH-indazole; 4-Fluoro-6-bromoindazol-3-ol
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoro-3-Hydroxyindazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations for industrial chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.