Description

4-Bromo-3-Iodo-6-Fluoro-(1H)Indazole is a high-value, multi-halogenated indazole derivative, a crucial building block in modern organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in kinase inhibitor and pesticide discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its halogen-rich scaffold.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probe Development: Utilized in creating molecular probes and ligands for studying enzyme function and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed Suzuki, Stille, and Sonogashira cross-coupling reactions to form complex biaryl structures.
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	4-Bromo-3-Iodo-6-Fluoro-(1H)Indazole
CAS No.	887567-87-5
Molecular Formula	C7H3BrFIN2
Molecular Weight	340.92 g/mol
Synonyms	4-Bromo-3-iodo-6-fluoro-1H-indazole; 6-Fluoro-4-bromo-3-iodo-1H-indazole; 1H-Indazole, 4-bromo-3-iodo-6-fluoro-; 4-Bromo-3-iodo-6-fluoroindazole; 887567-87-5; AI3-63535; AKOS040751947; BRN 15241753; CTK8G8129; F2198-1425; FT-0773295; NSC 937841; SCHEMBL21847677; ZINC000257840759
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Iodo-6-Fluoro-(1H)Indazole is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.