Description

4,6-Difluoro-3-Iodoindazole is a high-value fluorinated and iodinated indazole derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for medicinal chemistry research, particularly in the development of targeted pharmaceuticals and bioactive compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex heterocyclic motifs into their molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides with enhanced activity and selectivity.
• Material Science Precursor: Employed in the creation of specialized organic electronic materials and liquid crystals.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and diagnostic agents due to its halogen handles for further functionalization.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis: A valuable building block for generating diverse compound libraries in high-throughput screening programs.

Basic Information

Product Name	4,6-Difluoro-3-Iodoindazole
CAS No.	887567-79-5
Molecular Formula	C7H3F2IN2
Molecular Weight	279.97 g/mol
Synonyms	3-Iodo-4,6-difluoro-1H-indazole; 4,6-Difluoro-1H-indazole, 3-iodo-; 1H-Indazole, 4,6-difluoro-3-iodo-; 4,6-Difluoro-3-iodo-1H-indazole; 3-Iodo-4,6-difluoroindazole; 887567-79-5; AI3-32973
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-3-Iodoindazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.