Description

2-(Boc-Amino)-4-Methylthiophene is a high-purity, protected amino acid derivative and a key thiophene-based building block. This compound is essential for the synthesis of complex molecules, offering a versatile and reactive site for peptide coupling and further functionalization under mild conditions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing thiophene heterocycles.
• Peptide Synthesis: Serves as a Boc-protected amino acid derivative for solid-phase and solution-phase peptide synthesis, enabling the incorporation of thiophene motifs.
• Agrochemical Research: Used as a building block in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the creation of functionalized monomers for conductive polymers, organic semiconductors, and advanced polymeric materials.
• Chemical Biology: Useful for labeling and bioconjugation strategies, creating probes and linkers for studying biological systems.
• Custom Synthesis & Scale-Up: A vital starting material for contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects from milligram to kilogram scale.

Basic Information

Item	Detail
Product Name	2-(Boc-Amino)-4-Methylthiophene
CAS No.	887475-43-6
Molecular Formula	C11H17NO2S
Molecular Weight	227.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-4-methylthiophene; 2-(tert-Butoxycarbonylamino)-4-methylthiophene; Boc-4-methyl-2-thienylamine; N-Boc-2-amino-4-methylthiophene; tert-Butyl (4-methylthiophen-2-yl)carbamate; 2-Amino-4-methylthiophene, N-Boc protected; Boc-AMT; N-(tert-Butoxycarbonyl)-4-methyl-2-thiophenamine
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-4-Methylthiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.