Description

3-[1-[5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinyl]-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	3-[1-[5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinyl]-1H-Indole
CAS No.	887418-66-8
Molecular Formula	C19H18F3N3
Molecular Weight	345.36 g/mol
Synonyms	1H-Indole, 3-[1-[5-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]-; 3-(1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-yl)-1H-indole; 3-[1-[5-(Trifluoromethyl)-2-pyridyl]-4-piperidyl]indole; 3-(1-(5-(Trifluoromethyl)-2-pyridinyl)-4-piperidinyl)-1H-indole; 887418-66-8; UNII-2K1V7GP32S
EINECS	Contact for details

Quality Control

Our 3-[1-[5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.