Description

Hexatriacontyl Methanethiosulfonate is a specialized long-chain alkyl methanethiosulfonate (MTS) reagent, a critical tool for site-directed chemical modification and crosslinking in advanced biochemical and materials science research. Its primary value lies in its ability to selectively introduce disulfide bonds or thiol-reactive groups onto specific sites within proteins, peptides, or synthetic polymers, enabling precise structural and functional studies. This high-purity compound is essential for researchers and developers in pharmaceutical R&D, bioconjugation, and nanotechnology, where controlled molecular assembly and labeling are paramount.

Application

• Site-Directed Spin Labeling (SDSL) in protein structure and dynamics analysis via EPR spectroscopy.
• Bioconjugation and Crosslinking for attaching probes, drugs, or other molecules to proteins and peptides.
• Membrane Protein Studies, utilizing its long hydrophobic chain to modify and anchor proteins within lipid bilayers.
• Polymer Functionalization to introduce reactive thiol groups into synthetic materials for further chemical modification.
• Development of Self-Assembled Monolayers (SAMs) on gold and other surfaces for sensor and device fabrication.
• Chemical Biology Tool for probing cysteine accessibility and protein-protein interactions.

Basic Information

Product Name	Hexatriacontyl Methanethiosulfonate
CAS No.	887406-39-5
Molecular Formula	C₃₇H₇₆O₂S₂
Molecular Weight	613.1 g/mol
Synonyms	MTS-C36; n-Hexatriacontyl methanethiosulfonate; 1-Hexatriacontyl methanethiosulfonate; Methanethiosulfonic acid S-hexatriacontyl ester; C36-MTS; S-Hexatriacontyl methanethiosulfonothioate; Long-chain MTS reagent
EINECS	Contact for details

Quality Control

Our Hexatriacontyl Methanethiosulfonate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.