Description

5-Cyclopropyl-Isoxazole-3-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique isoxazole-cyclopropyl scaffold enables the creation of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key synthon for constructing bioactive molecules, particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the isoxazole moiety.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and enzyme functions.
• Material Science Precursor: Potential building block for advanced organic materials and functional polymers requiring specific heterocyclic components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Cyclopropyl-Isoxazole-3-Carboxylic Acid Methyl Ester
CAS No.	887360-91-0
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	Methyl 5-cyclopropyl-1,2-oxazole-3-carboxylate; 5-Cyclopropyl-3-(methoxycarbonyl)isoxazole; 5-Cyclopropylisoxazole-3-carboxylic acid methyl ester; 3-Carbomethoxy-5-cyclopropylisoxazole; Methyl 5-cyclopropylisoxazole-3-carboxylate; 887360-91-0; 5-Cyclopropyl-3-methoxycarbonylisoxazole
EINECS	Contact for details

Quality Control

Our 5-Cyclopropyl-Isoxazole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.