Description

6-tert-Butyl-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized indole scaffold essential for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its indole core for potential herbicidal or fungicidal activity.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its conjugated system.
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical research to study protein interactions and enzyme inhibition.
• Academic & Contract Research: Serves as a versatile starting material in academic laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.
• Fine Chemical Synthesis: Utilized for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	6-tert-Butyl-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	887360-36-3
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.29 g/mol
Synonyms	Methyl 6-tert-butyl-1H-indole-2-carboxylate; 6-tert-Butylindole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 6-(1,1-dimethylethyl)-, methyl ester; Methyl 6-(tert-butyl)-1H-indole-2-carboxylate; 6-(tert-Butyl)-1H-indole-2-carboxylic Acid Methyl Ester; 6-tert-Butyl-1H-indole-2-carboxylic Acid Methyl Ester; 6-tert-Butylindole-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.