Description

12-(T-Boc-Amino)-1-Dodecyl Bromide is a high-purity, bifunctional organic building block featuring a protected amine group and a reactive alkyl bromide terminus. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, enabling the controlled introduction of long-chain alkyl functionalities. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as peptide modification, lipid conjugation, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs requiring long alkyl chain linkers.
• Peptide Modification: Used to introduce lipophilic chains onto peptides or proteins to alter their pharmacokinetic properties.
• Lipid Conjugation Chemistry: Serves as a reagent for creating lipid-drug conjugates or functionalized lipids for nanoparticle formulations.
• Polymer & Dendrimer Synthesis: Acts as a monomer or functionalization agent in the production of specialty polymers and dendrimers.
• Surface Functionalization: Employed to create self-assembled monolayers (SAMs) or to graft functional groups onto material surfaces.
• Agrochemical Synthesis: Intermediate in the development of surfactants, adjuvants, or active compounds with specific delivery properties.
• Crosslinking Agent: Utilized in the synthesis of crosslinked networks for gels or resins due to its bifunctional reactivity.
• Chemical Biology Probes: Foundation for creating probes that study membrane interactions or cellular uptake mechanisms.

Basic Information

Product Name	12-(T-Boc-Amino)-1-Dodecyl Bromide
CAS No.	887353-35-7
Molecular Formula	C₁₇H₃₄BrNO₂
Molecular Weight	364.36 g/mol
Synonyms	1-Bromo-12-[(tert-butoxycarbonyl)amino]dodecane; N-(11-Bromoundecyl)carbamic Acid tert-Butyl Ester; N-Boc-12-Aminododecyl Bromide; 12-(N-Boc-Amino)dodecyl Bromide; tert-Butyl (11-bromoundecyl)carbamate; Boc-NH-(CH2)12-Br; 12-(tert-Butoxycarbonylamino)dodecyl-1-bromide
EINECS	Contact for details

Quality Control

Our 12-(T-Boc-Amino)-1-Dodecyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and cGMP-grade material requirements where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is sensitive to strong acids and should be kept away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.