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10-(T-Boc-Amino)-1-Decylbromide CAS NO 887353-29-9
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CAS No.:887353-29-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
10-(T-Boc-Amino)-1-Decylbromide is a high-purity, bifunctional organic building block featuring a bromoalkyl chain and a tert-butoxycarbonyl (Boc)-protected amine group. This compound matters for its versatility in controlled molecular assembly, enabling the precise introduction of a ten-carbon spacer with a protected amine handle into complex structures. Pharmaceutical researchers and fine chemical manufacturers need it for applications in peptide mimetics, linker chemistry for bioconjugation, and as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.
Application
- Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in oncology and neurology.
- Peptide & Peptidomimetic Synthesis: Used to introduce hydrophobic spacers or protected amine functionalities into peptide chains.
- Bioconjugation & Linker Chemistry: Serves as a heterobifunctional linker for attaching drugs, dyes, or probes to antibodies, proteins, or nanoparticles.
- Material Science: Intermediate in the creation of functionalized surfaces, polymers, and dendrimers with specific amine reactivity.
- Chemical Biology Probes: Utilized in the development of activity-based probes and affinity labels for target identification.
- Protecting Group Strategy: The Boc group allows for orthogonal deprotection in multi-step synthetic sequences.
Basic Information
| Product Name | 10-(T-Boc-Amino)-1-Decylbromide |
| CAS No. | 887353-29-9 |
| Molecular Formula | C15H30BrNO2 |
| Molecular Weight | 336.31 g/mol |
| Synonyms | 1-Bromo-10-[(tert-butoxycarbonyl)amino]decane; 10-((tert-Butoxycarbonyl)amino)decyl bromide; N-(10-Bromodecyl)carbamic acid tert-butyl ester; N-Boc-1,10-diaminodecane hydrobromide (precursor form); Boc-NH-(CH2)10-Br; tert-Butyl (10-bromodecyl)carbamate; TBDMS (not applicable, but common search confusion); Amino-PEG10-bromide analog (structural analog). |
| EINECS | Contact for details |
Quality Control
Every batch of 10-(T-Boc-Amino)-1-Decylbromide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in cGMP and research applications where traceability and reliability are paramount.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. The compound is sensitive to strong acids and organic solvents; keep away from incompatible materials. Under these conditions, the product is stable for extended periods.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 10 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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