Description

2-Benzyloxy-5-Acetaminobenzenethiol is a specialized organic sulfur compound featuring a benzyl-protected phenol and an acetamido group, making it a valuable building block in advanced chemical synthesis. This compound is particularly significant for its role as a key intermediate in the development of complex molecules, including pharmaceuticals and functional materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific thiol and aromatic functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a protected thiol or phenolic ether moiety.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the benzenethiol structure can contribute to biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers, ligands for catalysis, or advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block in organic chemistry for coupling reactions, nucleophilic substitutions, and as a protecting group strategy component.
• Ligand and Catalyst Development: Useful for creating novel chelating ligands in coordination chemistry and catalysis due to the presence of sulfur and oxygen donor atoms.

Basic Information

Product Name	2-Benzyloxy-5-Acetaminobenzenethiol
CAS No.	887352-92-3
Molecular Formula	C15H15NO2S
Molecular Weight	273.35 g/mol
Synonyms	N-[5-(Benzyloxy)-2-mercaptophenyl]acetamide; 5-(Benzyloxy)-2-mercaptoacetanilide; 2-Mercapto-5-(phenylmethoxy)acetanilide; 2-Benzyloxy-5-acetamidobenzenethiol; 2-Benzyloxy-5-acetamidothiophenol; Acetamide, N-[5-(benzyloxy)-2-mercaptophenyl]-; 887352-92-3
EINECS	Contact for details

Quality Control

Every batch of 2-Benzyloxy-5-Acetaminobenzenethiol is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the rigorous standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed under positive pressure of inert gas after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.