Description

3-Bromo-7-Methyl-1-(p-Toluenesulfonyl)Indole is a high-purity, synthetically valuable indole derivative, specifically functionalized with bromine and a tosyl protecting group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides due to its bioactive indole core.
• Organic Synthesis Building Block: The bromine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck), while the tosyl group acts as a protective moiety.
• Material Science: Investigated as a monomer or dopant for creating specialized organic electronic materials and functional polymers.
• Academic & R&D: Essential for methodological studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	3-Bromo-7-Methyl-1-(p-Toluenesulfonyl)Indole
CAS No.	887338-40-1
Molecular Formula	C₁₆H₁₄BrNO₂S
Molecular Weight	364.26 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-3-bromo-7-methyl-1H-indole; 3-Bromo-7-methyl-1-tosylindole; 3-Bromo-7-methyl-1H-indole-1-sulfonic acid 4-methylphenyl ester; 3-Bromo-7-methyl-1-(4-methylphenylsulfonyl)indole; 3-Bromo-7-methyl-1-(tosyl)indole; 1-Tosyl-3-bromo-7-methylindole; 3-Bromo-7-methylindole-1-sulfonyl p-tolyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-7-Methyl-1-(p-Toluenesulfonyl)Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.