Description

2,3-Bis-Trifluoromethyl-Thieno[3,4-B][1,4]Dioxine-5,7-Dicarboxylic Acid is a high-value, multifunctional fluorinated heterocyclic building block. This compound is critical for introducing electron-withdrawing trifluoromethyl groups and specific heterocyclic architectures into advanced molecular frameworks. It is primarily sought after by R&D and process development teams in the pharmaceutical and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for introducing electron-deficient, lipophilic motifs that can enhance metabolic stability and membrane permeability.
• Organic Electronic Materials: Serves as a monomer or dopant in the development of conductive polymers, organic semiconductors, and non-fullerene acceptors for solar cells due to its electron-accepting properties.
• Agrochemical Research: Used in creating new active ingredients for crop protection, where the trifluoromethyl groups can improve biological activity and environmental persistence.
• Ligand Synthesis for Catalysis: Employed to construct sophisticated, fluorinated ligands for transition metal catalysts used in cross-coupling and other specialty reactions.
• High-Performance Polymer Modification: Incorporated into polymer backbones to impart specific properties like chemical resistance, thermal stability, or unique optical characteristics.

Basic Information

Product Name	2,3-Bis-Trifluoromethyl-Thieno[3,4-B][1,4]Dioxine-5,7-Dicarboxylic Acid
CAS No.	887268-15-7
Molecular Formula	C12H2F6O6S
Molecular Weight	412.20 g/mol
Synonyms	2,3-Bis(trifluoromethyl)thieno[3,4-b][1,4]dioxine-5,7-dicarboxylic acid; 5,7-Dicarboxy-2,3-bis(trifluoromethyl)thieno[3,4-b]-1,4-dioxin; Thienodioxinedicarboxylic acid, bis(trifluoromethyl) derivative; CAS 887268-15-7; 2,3-Bis(trifluoromethyl)-5,7-dicarboxythieno[3,4-b][1,4]dioxine
EINECS	Contact for details

Quality Control

Every batch of 2,3-Bis-Trifluoromethyl-Thieno[3,4-B][1,4]Dioxine-5,7-Dicarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. A detailed Certificate of Analysis (COA) confirming identity, purity (typically by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.