Description

2-[1-(2-Fluoro-Benzyl)-Piperidin-4-Yl]-1H-Benzoimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzimidazole-piperidine hybrid structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Key intermediate in the synthesis of potential kinase inhibitors for oncology research.
• Building block for the development of novel central nervous system (CNS) active compounds, including potential antipsychotics or cognitive enhancers.
• Precursor in medicinal chemistry programs targeting G-protein coupled receptors (GPCRs).
• Research chemical for studying structure-activity relationships (SAR) in benzimidazole-based pharmacophores.
• Starting material for custom synthesis services in contract pharmaceutical manufacturing.
• Reference standard for analytical method development and quality control in API production.

Basic Information

Product Name	2-[1-(2-Fluoro-Benzyl)-Piperidin-4-Yl]-1H-Benzoimidazole
CAS No.	887217-21-2
Molecular Formula	C19H20FN3
Molecular Weight	309.38 g/mol
Synonyms	2-[1-[(2-Fluorophenyl)methyl]piperidin-4-yl]-1H-benzimidazole; 1H-Benzimidazole, 2-[1-[(2-fluorophenyl)methyl]-4-piperidinyl]-; 2-(1-(2-Fluorobenzyl)piperidin-4-yl)-1H-benzo[d]imidazole; 2-(1-(2-Fluorobenzyl)-4-piperidyl)-1H-benzimidazole; 887217-21-2; 2-[1-(2-Fluorobenzyl)piperidin-4-yl]-1H-benzoimidazole
EINECS	Contact for details

Quality Control

Our 2-[1-(2-Fluoro-Benzyl)-Piperidin-4-Yl]-1H-Benzoimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.